Paulo Martel @ University of Algarve

Paulo Martel is a teacher of Bioinformatics, Computational Biology, Structural Biochemistry and Enzimology at the Department of Biological Sciences and Bioengineering, Faculty of Sciences and Technology. He is a theoretical biochemist working in computer modelling and simulation of biomolecules, with an emphasis in the study of electrostatic effects on protein structure and function and the development of new methods for macromolecular electrostatic calculations.

Between 2004-2014 he was scientific coordinator of a research unit at the University of Algarve, the Center for Structural and Molecular Biomedicine(CBME). This unit is now known as Centre of Biomedical Research (CBMR).

Research interests

• Protein structure and dynamics
• Modelling of electrostatics interactions in proteins
• Theoretical calculations of pKa values for protein residues
• Role of electrostatic interactions in protein structure and function
• Application of Biomolecular simulation methods to a diverse set of biological problems

Current research

• Structure-function relationships of elicitin proteins from Phytophthora oomycetes.
• Modelling and molecular evolution of Bone and matrix Gla proteins
• Molecular pharmacogenomics of P450 proteins - modelling the effect of SNP's.
• Effect of vanadate oligomers on the motor proteins myosin and actin.

Teaching

• Enzymology
• Structural Biochemistry
• Bioinformatics
• Biochemistry (Lic.Enfermagem)
• Molecular Modelling in Drug Design

Side projects

• Soundplot: a Python tool for music visualization.
• Interactive Python tools for scientic education.
• Scientific applications of Virtual Reality.

Materiais de apoio a disciplinas:

• Bioinformatica
• Modelação Molecular no Desenho de Fármacos
• Enzimologia
• Bioquímica Estrutural
• Biologia Computacional